UBXN6

Across TCGA cell cohorts, UBXN6 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible UBXN6-associated genes across cancer lineages are PRSS58, CNGA2, and GALP. Each is linked with UBXN6 in more than 1 cancer types. Because this analysis shows association rather than direction, both UBXN6-to-partner and partner-to-UBXN6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRSS58 grouped by UBXN6-low versus UBXN6-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBXN6→partner) and Y-score (partner→UBXN6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	PRSS58 →	+0.035	+4.266	<.001	.004	3	1
BLOOD_Leukemia	CNGA2 →	+0.099	+5.539	<.001	.003	3	1
BLOOD_Leukemia	GALP →	+0.068	+5.201	<.001	.006	3	1
BLOOD_Leukemia	IFNA4 →	+0.058	+4.922	<.001	.009	3	1
STOMACH	GPR171 →	+0.023	+4.129	.005	.007	3	1
STOMACH	SSX7 →	+0.325	+4.285	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

PRSS58 by UBXN6 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →