UBXN4

Across TCGA cell cohorts, UBXN4 mutation is significantly associated with the drug of many other genes, with 13 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible UBXN4-associated genes across cancer lineages are Bromosporine, 123829, and Sabutoclax. Each is linked with UBXN4 in more than 1 cancer types. Because this analysis shows association rather than direction, both UBXN4-to-partner and partner-to-UBXN4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Bromosporine grouped by UBXN4-low versus UBXN4-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBXN4→partner) and Y-score (partner→UBXN4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Bromosporine →	+0.346	+2.649	.044	.046	3	1
LARGE_INTESTINE	123829 →	+0.685	+2.649	.018	.046	3	1
LARGE_INTESTINE	Sabutoclax →	+0.520	+2.769	.013	.040	3	1
LARGE_INTESTINE	KRAS (G12C) Inhibitor-12 →	+0.702	+2.646	.004	.047	3	1
LARGE_INTESTINE	PRT062607 →	+0.721	+2.777	.003	.030	2	1
LARGE_INTESTINE	Dinaciclib →	+0.540	+2.646	.036	.047	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

Bromosporine by UBXN4 expression — LARGE_INTESTINE

Explore this box plot interactively →