Across TCGA patient cohorts, UBXN2B mutation is significantly associated with the total protein of many other genes, with 23 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UBXN2B-associated genes across cancer lineages are eEF2, EGFR_pY1068, and JNK_pT183_Y185. Each is linked with UBXN2B in more than 1 cancer types. Because this analysis shows association rather than direction, both UBXN2B-to-partner and partner-to-UBXN2B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBXN2B→partner) and Y-score (partner→UBXN2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.304	+2.321	.026	.033	3	1
UCEC	EGFR_pY1068 →	-0.308	-3.700	.001	.001	3	1
UCEC	JNK_pT183_Y185 →	-0.148	-2.321	.022	.034	3	1
UCEC	mTOR_pS2448 →	-0.137	-2.446	.016	.018	3	1
UCEC	p62 Lck ligand →	+0.366	+1.710	.003	.025	3	1
UCEC	PCNA →	+0.275	+2.906	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

Exploration

UBXN2B survival (RNA) · tumor vs normal (RNA) · all UBXN2B data types