UBXN11

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, UBXN11 mutation is significantly associated with the RNA expression of many other genes, with 1,548 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UBXN11-associated genes across cancer lineages are LINC01072, HMGN1P12, and RNU6-841P. Each is linked with UBXN11 in more than 1 cancer types. Because this analysis shows association rather than direction, both UBXN11-to-partner and partner-to-UBXN11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01072 grouped by UBXN11-low versus UBXN11-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBXN11→partner) and Y-score (partner→UBXN11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECLINC01072 →+0.115+2.126<.001.00232
BLCAHMGN1P12 →+0.327+3.851.005.00832
CESCRNU6-841P →+0.449+6.837<.001<.00132
SKCMCNOT7P2 →+0.046+3.953.001.00532
CESCMIR548O2 →+0.420+5.669<.001.00332
UCECRNU5E-9P →+0.156+3.595<.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,548 associations by consensus.

LINC01072 by UBXN11 expression — UCEC

Box plot of LINC01072 in UBXN11-low vs UBXN11-high samples in UCEC.

Explore this box plot interactively →

Exploration