UBXN11

Across TCGA cell cohorts, UBXN11 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible UBXN11-associated genes across cancer lineages are MAGEB4, TBC1D21, and GSG1L2. Each is linked with UBXN11 in more than 1 cancer types. Because this analysis shows association rather than direction, both UBXN11-to-partner and partner-to-UBXN11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MAGEB4 grouped by UBXN11-low versus UBXN11-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBXN11→partner) and Y-score (partner→UBXN11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	MAGEB4 →	+0.013	+6.022	<.001	.001	3	1
LARGE_INTESTINE	TBC1D21 →	+0.008	+3.700	<.001	.009	3	1
LARGE_INTESTINE	GSG1L2 →	+0.011	+3.700	<.001	.009	3	1
BLOOD_Leukemia	SYNPR →	+0.042	+4.409	<.001	.005	3	1
BLOOD_Leukemia	GFRAL →	+0.025	+5.569	<.001	.001	3	1
BLOOD_Leukemia	LRRTM3 →	+0.004	+4.539	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

MAGEB4 by UBXN11 expression — SKIN

Explore this box plot interactively →