Across TCGA pan-cancer cohorts, UBTFL8 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of UBTFL8’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where UBTFL8 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types UBTFL8 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

HNSC, LUAD, and KICH are the cancer types where UBTFL8 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in UBTFL8 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	All	+0.053	<.001	10	view →
LUAD	Female	All	+0.056	.016	4	view →
KICH	All	All	−0.014	.028	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: UBTFL8 RNA expression & survival · all UBTFL8 data types