UBTFL2

Across TCGA pan-cancer cohorts, UBTFL2 RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated UBTFL2 data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher UBTFL2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated UBTFL2 expression acts as an unfavorable survival marker, although some lineages such as ESCA show a favorable association.

KIRP, LUSC, and DLBC are the cancer types where UBTFL2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	OS	Tertile	II,III,IV	0.170	0.751	<.001	69	view →
LUSC	DFS	Tertile	III,IV	0.184	0.736	.016	36	view →
DLBC	OS	Tertile	III,IV	0.175	0.874	.025	36	view →
SKCM	DFS	Tertile	II,III,IV	0.126	0.686	<.001	30	view →
UCEC	DFS	Tertile	All	0.729	0.901	.016	24	view →
STAD	DFS	Tertile	IV	0.083	0.379	.001	18	view →
PCPG	DFS	Tertile	All	0.070	0.936	<.001	18	view →
LGG	OS	Tertile	All	0.599	0.839	.012	12	view →
CHOL	OS	Tertile	All	0.155	0.725	.029	9	view →
ESCA	OS	Quartile	III,IV	0.782	0.370	.031	5	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

UBTFL2–KIRP (OS)

Open the KIRP breakdown →