UBTFL11

Across TCGA patient cohorts, UBTFL11 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,354 significant associations in total. STAD shows the largest number of these associations.

The most reproducible UBTFL11-associated GO terms across cancer lineages are Positive regulation of double-strand break repair, Establishment of RNA localization, and Positive regulation of proteolysis involved in protein catabolic process. Each is linked with UBTFL11 in more than 9 cancer types. Because this analysis shows association rather than direction, both UBTFL11-to-partner and partner-to-UBTFL11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of double-strand break repair grouped by UBTFL11-low versus UBTFL11-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UBTFL11→partner) and Y-score (partner→UBTFL11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Positive regulation of double-strand break repair →	+0.069	+0.069	<.001	.002	3	10
STAD	Establishment of RNA localization →	+0.066	+0.098	<.001	<.001	3	10
ESCA	Positive regulation of proteolysis involved in protein catabolic process →	+0.066	+0.112	<.001	.001	3	10
STAD	ATP synthesis coupled electron transport →	+0.082	+0.121	<.001	<.001	3	10
STAD	Nucleobase-containing compound transport →	+0.059	+0.104	<.001	<.001	3	9
ESCA	Respiratory electron transport chain →	+0.082	+0.121	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,354 associations by consensus.

Positive regulation of double-strand break repair by UBTFL11 expression — ESCA

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