UBTFL10

Across TCGA pan-cancer cohorts, UBTFL10 RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated UBTFL10 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher UBTFL10 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated UBTFL10 expression acts as an unfavorable survival marker, although some lineages such as LIHC and KIRC show a favorable association.

HNSC, LIHC, and PAAD are the cancer types where UBTFL10 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	All	0.165	0.610	.001	96	view →
LIHC	OS	Tertile	All	0.785	0.483	<.001	44	view →
PAAD	OS	Tertile	All	0.028	0.591	<.001	36	view →
UCEC	OS	Tertile	All	0.826	0.930	.001	36	view →
LUSC	OS	Tertile	III,IV	0.415	0.708	.023	21	view →
STAD	OS	Tertile	All	0.444	0.734	.035	18	view →
LAML	DFS	Tertile	All	0.165	0.581	.034	18	view →
BRCA	DFS	Tertile	II,III,IV	0.701	0.891	.022	12	view →
KIRC	DFS	Tertile	All	0.761	0.605	.045	3	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

UBTFL10–HNSC (OS)

Open the HNSC breakdown →