UBTD1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, UBTD1 mutation is significantly associated with the RNA expression of many other genes, with 1,344 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UBTD1-associated genes across cancer lineages are MIR6803, PSAT1P4, and HPRT1P2. Each is linked with UBTD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both UBTD1-to-partner and partner-to-UBTD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6803 grouped by UBTD1-low versus UBTD1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBTD1→partner) and Y-score (partner→UBTD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMIR6803 →+0.172+4.671<.001.00232
UCECPSAT1P4 →+0.205+2.300<.001.00132
UCECHPRT1P2 →+0.053+3.220<.001.00532
CESCRNU6-128P →+0.377+5.306<.001.00631
CESCRNU1-4 →+0.302+6.837<.001<.00131
CESCKRTAP12-4 →+0.123+6.342<.001.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,344 associations by consensus.

MIR6803 by UBTD1 expression — UCEC

Box plot of MIR6803 in UBTD1-low vs UBTD1-high samples in UCEC.

Explore this box plot interactively →

Exploration