UBR5

Across TCGA patient cohorts, UBR5 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,471 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible UBR5-associated proteins across cancer lineages are RBM12B, NUDCD1, and CHRAC1. Each is linked with UBR5 in more than 5 cancer types. Because this analysis shows association rather than direction, both UBR5-to-partner and partner-to-UBR5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UBR5 versus RBM12B in GBM, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (UBR5→partner) and Y-score (partner→UBR5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RBM12B →	+0.254	+0.171	<.001	<.001	3	5
COAD	NUDCD1 →	+0.418	+0.820	<.001	<.001	3	5
LSCC	CHRAC1 →	+0.445	+0.514	<.001	<.001	3	5
LSCC	AGO2 →	+0.254	+0.626	<.001	<.001	3	5
LSCC	FOXK1 →	+0.234	+0.306	<.001	<.001	3	5
BRCA	FKBP11 →	-0.683	-0.620	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,471 associations by consensus.

UBR5 vs RBM12B — GBM

Explore this scatter interactively →