UBR4

Across TCGA patient cohorts, UBR4 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,797 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible UBR4-associated proteins across cancer lineages are RCC2, NXF1, and PPP1R8. Each is linked with UBR4 in more than 4 cancer types. Because this analysis shows association rather than direction, both UBR4-to-partner and partner-to-UBR4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UBR4 versus RCC2 in LSCC, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (UBR4→partner) and Y-score (partner→UBR4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RCC2 →	+0.448	+0.461	<.001	<.001	3	5
GBM	NXF1 →	+0.274	+0.330	<.001	<.001	3	4
GBM	PPP1R8 →	+0.176	+0.271	.002	.003	3	4
GBM	KHDRBS1 →	+0.329	+0.344	<.001	<.001	3	4
BRCA	LYPLA2 →	+0.259	+0.432	<.001	<.001	3	4
LSCC	WRNIP1 →	+0.329	+0.354	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,797 associations by consensus.

UBR4 vs RCC2 — LSCC

Explore this scatter interactively →