UBR4

Across TCGA patient cohorts, UBR4 protein abundance is significantly associated with the RNA expression of many other genes, with 6,643 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible UBR4-associated genes across cancer lineages are KCMF1, GNB1, and S100B. Each is linked with UBR4 in more than 5 cancer types. Because this analysis shows association rather than direction, both UBR4-to-partner and partner-to-UBR4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UBR4 versus KCMF1 in HNSC, with a Pearson correlation of 0.26.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBR4→partner) and Y-score (partner→UBR4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	KCMF1 →	+0.522	+0.181	.001	<.001	3	6
LUAD	GNB1 →	+0.390	+0.177	<.001	<.001	3	5
LUAD	S100B →	-1.366	-0.164	<.001	<.001	3	4
OV	DDOST →	+0.373	+0.149	.004	<.001	3	4
OV	MAD2L2 →	+0.639	+0.172	.005	<.001	3	4
LSCC	LZIC →	+0.718	+0.209	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,643 associations by consensus.

UBR4 vs KCMF1 — HNSC

Explore this scatter interactively →