UBR2

Across TCGA patient cohorts, UBR2 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,513 significant associations in total. GBM shows the largest number of these associations.

The most reproducible UBR2-associated proteins across cancer lineages are CD2AP, KLC4, and ZNF318. Each is linked with UBR2 in more than 5 cancer types. Because this analysis shows association rather than direction, both UBR2-to-partner and partner-to-UBR2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UBR2 versus CD2AP in PDAC, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (UBR2→partner) and Y-score (partner→UBR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	CD2AP →	+0.320	+0.302	<.001	<.001	3	6
PDAC	KLC4 →	+0.330	+0.268	<.001	<.001	3	5
LSCC	ZNF318 →	+0.277	+0.350	<.001	<.001	3	4
LSCC	WRNIP1 →	+0.545	+0.347	<.001	<.001	3	4
PDAC	PPP2R5D →	+0.321	+0.307	<.001	<.001	3	4
OV	ACBD3 →	-0.185	-0.464	.004	.006	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,513 associations by consensus.

UBR2 vs CD2AP — PDAC

Explore this scatter interactively →