UBR2

Across TCGA patient cohorts, UBR2 protein abundance is significantly associated with the RNA expression of many other genes, with 10,291 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible UBR2-associated genes across cancer lineages are RPL7L1, MAD2L1BP, and TBCC. Each is linked with UBR2 in more than 6 cancer types. Because this analysis shows association rather than direction, both UBR2-to-partner and partner-to-UBR2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UBR2 versus RPL7L1 in LSCC, with a Pearson correlation of 0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBR2→partner) and Y-score (partner→UBR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RPL7L1 →	+0.603	+0.139	<.001	<.001	3	7
OV	MAD2L1BP →	+0.667	+0.238	.001	.002	3	5
LSCC	TBCC →	+0.580	+0.176	<.001	<.001	3	5
LSCC	MED20 →	+0.680	+0.161	<.001	<.001	3	4
HNSC	MRPS10 →	+0.644	+0.217	.001	<.001	2	5
LSCC	HSP90AB1 →	+0.642	+0.159	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,291 associations by consensus.

UBR2 vs RPL7L1 — LSCC

Explore this scatter interactively →