UBQLNL

Across TCGA pan-cancer cohorts, UBQLNL Mutation is linked to patient survival in 6 of 34 cancer types, making it a survival-associated UBQLNL data layer compared with 20 for mass-spec protein.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher UBQLNL Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated UBQLNL expression acts as an unfavorable survival marker, although some lineages such as LUSC show a favorable association.

ESCA, STAD, and BLCA are the cancer types where UBQLNL Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	OS	Median	II,III,IV	0.271	0.711	<.001	30	view →
STAD	OS	Median	IV	0.074	0.510	<.001	18	view →
BLCA	DFS	Median	IV	0.147	0.479	.020	6	view →
PRAD	DFS	Median	All	0.085	0.774	<.001	6	view →
SARC	DFS	Median	All	0.006	0.591	<.001	3	view →
LUSC	DFS	Median	All	1.000	0.654	.049	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

UBQLNL–ESCA (OS)

Open the ESCA breakdown →