UBQLN4

Across TCGA patient cohorts, UBQLN4 RNA expression is significantly associated with the protein abundance of many other proteins, with 22,172 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible UBQLN4-associated proteins across cancer lineages are RPRD2, C1orf35, and CDC73. Each is linked with UBQLN4 in more than 7 cancer types. Because this analysis shows association rather than direction, both UBQLN4-to-partner and partner-to-UBQLN4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UBQLN4 versus RPRD2 in HNSC, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (UBQLN4→partner) and Y-score (partner→UBQLN4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RPRD2 →	+0.353	+0.532	<.001	<.001	3	8
GBM	C1orf35 →	+0.457	+0.546	.001	<.001	3	8
GBM	CDC73 →	+0.344	+0.533	<.001	<.001	3	8
LSCC	DHX9 →	+0.313	+0.764	<.001	<.001	3	8
BRCA	GATAD2B →	+0.365	+0.547	<.001	<.001	3	8
HNSC	RPS27L →	-0.516	-0.474	.001	.009	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,172 associations by consensus.

UBQLN4 vs RPRD2 — HNSC

Explore this scatter interactively →