UBQLN4

Across TCGA cell cohorts, UBQLN4 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,663 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible UBQLN4-associated GO terms across cancer lineages are Epigenetic regulation of gene expression, Regulation of DNA repair, and Negative regulation of gene expression, epigenetic. Each is linked with UBQLN4 in more than 15 cancer types. Because this analysis shows association rather than direction, both UBQLN4-to-partner and partner-to-UBQLN4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Epigenetic regulation of gene expression grouped by UBQLN4-low versus UBQLN4-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UBQLN4→partner) and Y-score (partner→UBQLN4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Epigenetic regulation of gene expression →	+0.065	+0.717	<.001	.003	3	16
BONE	Regulation of DNA repair →	+0.076	+0.887	.006	.009	3	14
SOFT_TISSUE	Negative regulation of gene expression, epigenetic →	+0.063	+1.124	<.001	<.001	3	14
LUNG_SCLC	Positive regulation of double-strand break repair →	+0.079	+0.647	<.001	<.001	3	13
STOMACH	Regulation of nucleotide-excision repair →	+0.131	+0.698	.001	<.001	3	13
LUNG_NSCLC_LUSC	Positive regulation of cell fate commitment →	+0.219	+0.795	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,663 associations by consensus.

Epigenetic regulation of gene expression by UBQLN4 expression — OVARY

Explore this box plot interactively →