UBQLN4

Across TCGA cell cohorts, UBQLN4 mutation is significantly associated with the RNA expression of many other genes, with 35 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible UBQLN4-associated genes across cancer lineages are SLC32A1, NPFFR1, and TGM6. Each is linked with UBQLN4 in more than 1 cancer types. Because this analysis shows association rather than direction, both UBQLN4-to-partner and partner-to-UBQLN4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC32A1 grouped by UBQLN4-low versus UBQLN4-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBQLN4→partner) and Y-score (partner→UBQLN4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	SLC32A1 →	+0.691	+3.901	<.001	.006	3	1
BLOOD_Leukemia	NPFFR1 →	+0.015	+4.037	<.001	.004	3	1
BLOOD_Leukemia	TGM6 →	+0.018	+4.984	<.001	.002	3	1
BLOOD_Leukemia	C16orf92 →	+0.148	+4.037	<.001	.004	3	1
BLOOD_Leukemia	OR13J1 →	+0.126	+3.774	.001	.008	3	1
BLOOD_Leukemia	TACR3 →	+0.030	+4.060	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 35 associations by consensus.

SLC32A1 by UBQLN4 expression — BLOOD_Leukemia

Explore this box plot interactively →