Across TCGA patient cohorts, UBQLN2 mutation is significantly associated with the RNA expression of many other genes, with 3,718 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UBQLN2-associated genes across cancer lineages are RPL22P6, NDUFAF6, and TRAT1. Each is linked with UBQLN2 in more than 1 cancer types. Because this analysis shows association rather than direction, both UBQLN2-to-partner and partner-to-UBQLN2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBQLN2→partner) and Y-score (partner→UBQLN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RPL22P6 →	+0.097	+4.289	<.001	.007	3	2
UCEC	NDUFAF6 →	+0.288	+1.551	.002	<.001	3	2
UCEC	TRAT1 →	+0.286	+1.733	.002	<.001	3	2
UCEC	ASNS →	+0.596	+1.238	<.001	.006	3	2
UCEC	WDR62 →	+0.495	+2.343	<.001	<.001	3	2
COAD	IGHD6-6 →	+1.149	+3.681	.004	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,718 associations by consensus.

Exploration

UBQLN2 survival (RNA) · tumor vs normal (RNA) · all UBQLN2 data types