UBP1

Across TCGA cell cohorts, UBP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,445 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible UBP1-associated GO terms across cancer lineages are Regulation of double-strand break repair via homologous recombination, Double-strand break repair via nonhomologous end joining, and Regulation of double-strand break repair. Each is linked with UBP1 in more than 16 cancer types. Because this analysis shows association rather than direction, both UBP1-to-partner and partner-to-UBP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of double-strand break repair via homologous recombination grouped by UBP1-low versus UBP1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UBP1→partner) and Y-score (partner→UBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Regulation of double-strand break repair via homologous recombination →	+0.094	+1.436	<.001	<.001	3	17
OVARY	Double-strand break repair via nonhomologous end joining →	+0.050	+0.995	<.001	<.001	3	17
URINARY_TRACT	Regulation of double-strand break repair →	+0.069	+0.963	<.001	.001	3	16
BLOOD_Lymphoma	Regulation of mRNA catabolic process →	+0.066	+1.068	<.001	<.001	3	15
BREAST	Regulation of DNA repair →	+0.058	+0.864	<.001	.001	3	15
BLOOD_Lymphoma	Nucleosome disassembly →	+0.175	+1.241	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,445 associations by consensus.

Regulation of double-strand break repair via homologous recombination by UBP1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →