UBP1

Across TCGA cell cohorts, UBP1 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible UBP1-associated genes across cancer lineages are PITX3, PRMT8, and OR56A1. Each is linked with UBP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both UBP1-to-partner and partner-to-UBP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PITX3 grouped by UBP1-low versus UBP1-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBP1→partner) and Y-score (partner→UBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	PITX3 →	+0.314	+3.736	<.001	.009	3	1
BLOOD_Lymphoma	PRMT8 →	+0.157	+4.321	<.001	.002	3	1
BLOOD_Lymphoma	OR56A1 →	+0.025	+4.938	.003	<.001	3	1
BLOOD_Lymphoma	TMEM132C →	+0.360	+3.736	<.001	.009	3	1
BLOOD_Lymphoma	PRAMEF33 →	+0.007	+4.058	<.001	.009	3	1
BLOOD_Lymphoma	KRTAP9-2 →	+0.026	+4.662	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

PITX3 by UBP1 expression — BLOOD_Lymphoma

Explore this box plot interactively →