Across TCGA pan-cancer cohorts, UBOX5 Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated UBOX5 data layer compared with 24 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher UBOX5 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated UBOX5 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

LUAD, UCEC, and LIHC are the cancer types where UBOX5 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	All	0.433	0.837	<.001	46	view →
UCEC	DFS	Median	All	1.000	0.624	.006	34	view →
LIHC	OS	Median	All	0.156	0.709	<.001	21	view →
ESCA	OS	Median	II,III,IV	0.216	0.702	.014	6	view →
COAD	OS	Median	III,IV	0.168	0.691	.041	6	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: UBOX5 tumor-vs-normal RNA expression · all UBOX5 data types