Across TCGA pan-cancer cohorts, UBOX5 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated UBOX5 data layer compared with 24 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher UBOX5 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated UBOX5 expression acts as an unfavorable survival marker, although some lineages such as LUAD and CCRCC show a favorable association.

LUAD, CCRCC, and PDAC are the cancer types where UBOX5 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Median	All	0.859	0.538	.008	12	view →
CCRCC	OS	Median	All	0.959	0.727	.006	10	view →
PDAC	OS	Tertile	II,III,IV	0.905	0.198	.023	7	view →
LSCC	DFS	Quartile	All	1.000	0.892	.018	3	view →
HNSC	OS	Tertile	IV	0.661	0.927	.029	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: UBOX5 tumor-vs-normal RNA expression · all UBOX5 data types