Across TCGA patient cohorts, UBOX5 mutation is significantly associated with the total protein of many other genes, with 44 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UBOX5-associated genes across cancer lineages are INPP4B, 14-3-3_beta, and eEF2. Each is linked with UBOX5 in more than 1 cancer types. Because this analysis shows association rather than direction, both UBOX5-to-partner and partner-to-UBOX5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBOX5→partner) and Y-score (partner→UBOX5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	INPP4B →	-0.325	-1.571	.005	.019	3	2
UCEC	14-3-3_beta →	-0.117	-2.780	.001	.003	3	1
UCEC	eEF2 →	+0.360	+3.459	.005	.005	3	1
UCEC	EGFR_pY1068 →	-0.251	-1.584	.005	.019	3	1
UCEC	A-Raf_pS299 →	-0.138	-2.459	.001	.019	3	1
UCEC	ERK2 →	+0.233	+2.321	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 44 associations by consensus.

Exploration

UBOX5 survival (RNA) · tumor vs normal (RNA) · all UBOX5 data types