UBOX5-AS1

Across TCGA pan-cancer cohorts, UBOX5-AS1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated UBOX5-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher UBOX5-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated UBOX5-AS1 expression acts as an unfavorable survival marker, although some lineages such as ACC and PAAD show a favorable association.

KIRC, ACC, and PAAD are the cancer types where UBOX5-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	All	0.552	0.750	<.001	109	view →
ACC	DFS	Median	All	0.916	0.551	<.001	45	view →
PAAD	DFS	Median	All	0.393	0.188	<.001	41	view →
PRAD	DFS	Median	All	0.633	0.911	<.001	24	view →
UVM	OS	Median	All	0.800	1.000	.030	19	view →
MESO	DFS	Tertile	All	0.283	0.759	.001	18	view →
LUAD	DFS	Tertile	IV	0.240	1.000	.011	18	view →
LGG	DFS	Quartile	All	0.614	0.804	<.001	16	view →
SKCM	DFS	Tertile	III,IV	0.105	0.436	.007	15	view →
LAML	DFS	Tertile	All	0.547	0.300	.009	12	view →
LIHC	DFS	Quartile	All	0.448	0.645	.004	12	view →
BRCA	DFS	Median	IV	0.454	0.185	.018	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

UBOX5-AS1–KIRC (DFS)

Open the KIRC breakdown →