UBN2

Across TCGA pan-cancer cohorts, UBN2 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated UBN2 data layer compared with 25 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher UBN2 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated UBN2 expression acts as an unfavorable survival marker, although some lineages such as UCEC and LSCC show a favorable association.

UCEC, LSCC, and LUAD are the cancer types where UBN2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	II,III,IV	0.946	0.446	.001	36	view →
LSCC	OS	Tertile	All	0.963	0.719	.005	19	view →
LUAD	OS	Tertile	II,III,IV	1.000	0.854	.019	7	view →
HNSC	DFS	Median	IV	1.000	0.413	.033	6	view →
CCRCC	OS	Median	III,IV	0.485	1.000	.036	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

UBN2–UCEC (DFS)

Open the UCEC breakdown →