UBN2

Across TCGA cell cohorts, UBN2 protein abundance is significantly associated with the go_rna of many other GO terms, with 1,152 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible UBN2-associated GO terms across cancer lineages are L-lysine catabolic process, Cellular response to thyroid hormone stimulus, and Mismatch repair. Each is linked with UBN2 in more than 3 cancer types. Because this analysis shows association rather than direction, both UBN2-to-partner and partner-to-UBN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, L-lysine catabolic process grouped by UBN2-low versus UBN2-high in BLOOD_Leukemia.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UBN2→partner) and Y-score (partner→UBN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	L-lysine catabolic process →	-0.209	-1.020	<.001	.001	3	4
BLOOD_Leukemia	Cellular response to thyroid hormone stimulus →	+0.183	+0.822	<.001	.002	3	4
OESOPHAGUS	Mismatch repair →	-0.108	-2.027	.001	.008	3	3
LUNG_SCLC	Regulation of macrophage colony-stimulating factor signaling pathway →	+0.184	+0.802	.007	.002	3	3
BLOOD_Lymphoma	UMP metabolic process →	+0.123	+1.588	<.001	<.001	3	3
BLOOD_Lymphoma	UMP catabolic process →	+0.192	+1.051	.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,152 associations by consensus.

L-lysine catabolic process by UBN2 expression — BLOOD_Leukemia

Explore this box plot interactively →