UBN2

Across TCGA cell cohorts, UBN2 mutation is significantly associated with the RNA expression of many other genes, with 86 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible UBN2-associated genes across cancer lineages are OR13C7, PRSS54, and CETN1. Each is linked with UBN2 in more than 2 cancer types. Because this analysis shows association rather than direction, both UBN2-to-partner and partner-to-UBN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR13C7 grouped by UBN2-low versus UBN2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBN2→partner) and Y-score (partner→UBN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OR13C7 →	+0.011	+3.969	<.001	.009	3	3
LARGE_INTESTINE	PRSS54 →	+0.030	+3.345	<.001	.001	3	3
BREAST	CETN1 →	+0.003	+3.781	<.001	.009	3	2
BLOOD_Leukemia	IFNL3 →	+0.055	+3.339	.004	.006	3	2
URINARY_TRACT	TRIM49C →	+0.006	+5.087	<.001	.004	3	1
OESOPHAGUS	PPDPFL →	+0.033	+4.906	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 86 associations by consensus.

OR13C7 by UBN2 expression — BLOOD_Leukemia

Explore this box plot interactively →