UBN1

Across TCGA pan-cancer cohorts, UBN1 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated UBN1 data layer compared with 25 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher UBN1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated UBN1 expression acts as an unfavorable survival marker, although some lineages such as UCEC and LSCC show a favorable association.

UCEC, LSCC, and PDAC are the cancer types where UBN1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	All	0.943	0.782	.010	18	view →
LSCC	OS	Tertile	All	0.882	0.681	.024	12	view →
PDAC	OS	Tertile	All	0.286	0.560	.027	11	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

UBN1–UCEC (DFS)

Open the UCEC breakdown →