UBL7

Across TCGA pan-cancer cohorts, UBL7 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated UBL7 data layer compared with 21 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher UBL7 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated UBL7 expression acts as an unfavorable survival marker, although some lineages such as LSCC and UCEC show a favorable association.

LSCC, COAD, and UCEC are the cancer types where UBL7 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	OS	Median	II,III,IV	0.931	0.619	<.001	49	view →
COAD	DFS	Median	All	0.907	1.000	.038	18	view →
UCEC	DFS	Median	All	0.949	0.773	.006	10	view →
LUAD	OS	Tertile	III,IV	1.000	0.373	.034	6	view →
HNSC	OS	Quartile	III,IV	0.802	0.961	.028	5	view →
PDAC	OS	Quartile	III,IV	0.307	0.627	.047	2	view →
CCRCC	OS	Quartile	III,IV	0.742	1.000	.044	1	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

UBL7–LSCC (OS)

Open the LSCC breakdown →