UBL7-AS1

Across TCGA pan-cancer cohorts, UBL7-AS1 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of UBL7-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where UBL7-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types UBL7-AS1 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

HNSC, THCA, and KIRC are the cancer types where UBL7-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in UBL7-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	III,IV	+0.613	<.001	9	view →
THCA	All	All	−0.354	<.001	9	view →
KIRC	Male	All	+0.283	<.001	9	view →
LIHC	Male	All	+0.516	<.001	8	view →
BLCA	All	All	+0.745	<.001	7	view →
LUSC	Male	All	+0.685	<.001	6	view →
UCEC	All	II,III,IV	+0.586	.037	4	view →
STAD	Male	II,III,IV	+0.537	.003	4	view →
LUAD	Male	All	+0.352	.004	4	view →
CHOL	All	All	+0.799	<.001	3	view →
KICH	Female	All	−0.638	.004	3	view →
KIRP	All	IV	+0.357	.032	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

UBL7-AS1–HNSC

Open the HNSC breakdown →