UBL5P4

Across TCGA pan-cancer cohorts, UBL5P4 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated UBL5P4 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher UBL5P4 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated UBL5P4 expression acts as an unfavorable survival marker, although some lineages such as LAML and CESC show a favorable association.

UVM, BLCA, and ESCA are the cancer types where UBL5P4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Tertile	II,III,IV	0.203	0.743	<.001	72	view →
BLCA	OS	Tertile	III,IV	0.125	0.595	<.001	36	view →
ESCA	OS	Median	II,III,IV	0.622	0.763	.033	24	view →
LAML	DFS	Tertile	All	0.576	0.243	.001	22	view →
READ	DFS	Tertile	IV	0.190	0.638	.008	18	view →
OV	OS	Median	II,III,IV	0.652	0.723	.029	12	view →
CESC	DFS	Tertile	III,IV	1.000	0.347	.049	12	view →
MESO	DFS	Tertile	IV	0.071	0.359	.009	9	view →
STAD	OS	Tertile	IV	0.682	0.258	.040	9	view →
ACC	DFS	Tertile	II,III,IV	0.180	0.558	.032	9	view →
LIHC	DFS	Tertile	II,III,IV	0.133	0.433	.002	9	view →
LGG	OS	Tertile	All	0.690	0.813	.038	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

UBL5P4–UVM (OS)

Open the UVM breakdown →