UBIAD1

Across TCGA patient cohorts, UBIAD1 mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UBIAD1-associated genes across cancer lineages are aDC, CD8+ Tem, and Hepatocytes. Each is linked with UBIAD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both UBIAD1-to-partner and partner-to-UBIAD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, aDC grouped by UBIAD1-low versus UBIAD1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBIAD1→partner) and Y-score (partner→UBIAD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	aDC →	+0.108	+2.839	.003	.034	3	1
UCEC	CD8+ Tem →	+0.003	+4.606	<.001	.044	3	1
SKCM	Hepatocytes →	-0.017	-2.993	.034	.037	1	1
SKCM	MEP →	+0.034	+3.031	.029	.019	1	1
UCEC	Class-switched memory B-cells →	-0.058	-2.321	.044	.036	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

aDC by UBIAD1 expression — UCEC

Explore this box plot interactively →