UBIAD1

Across TCGA cell cohorts, UBIAD1 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible UBIAD1-associated genes across cancer lineages are FAM47A, FCN2, and MS4A18. Each is linked with UBIAD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both UBIAD1-to-partner and partner-to-UBIAD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM47A grouped by UBIAD1-low versus UBIAD1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBIAD1→partner) and Y-score (partner→UBIAD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	FAM47A →	+0.055	+4.922	<.001	.009	3	1
LARGE_INTESTINE	FCN2 →	+0.039	+4.415	<.001	.007	3	1
LARGE_INTESTINE	MS4A18 →	+0.028	+4.095	<.001	.009	3	1
LARGE_INTESTINE	F11 →	+0.073	+4.467	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

FAM47A by UBIAD1 expression — BLOOD_Leukemia

Explore this box plot interactively →