UBE3C

Across TCGA cell cohorts, UBE3C RNA expression is significantly associated with the go_rna of many other GO terms, with 3,705 significant associations in total. CNS shows the largest number of these associations.

The most reproducible UBE3C-associated GO terms across cancer lineages are Mitotic chromosome condensation, Nuclear export, and RNA export from nucleus. Each is linked with UBE3C in more than 12 cancer types. Because this analysis shows association rather than direction, both UBE3C-to-partner and partner-to-UBE3C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic chromosome condensation grouped by UBE3C-low versus UBE3C-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE3C→partner) and Y-score (partner→UBE3C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Mitotic chromosome condensation →	+0.122	+0.872	<.001	<.001	3	13
BLOOD_Leukemia	Nuclear export →	+0.069	+0.694	<.001	<.001	3	13
LARGE_INTESTINE	RNA export from nucleus →	+0.079	+0.629	<.001	<.001	3	12
LUNG_NSCLC_LUSC	Positive regulation of isotype switching to IgG isotypes →	+0.205	+1.078	<.001	<.001	3	12
SKIN	Peptidyl-serine phosphorylation →	+0.071	+0.882	<.001	<.001	3	12
SKIN	Peptidyl-serine modification →	+0.070	+0.900	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,705 associations by consensus.

Mitotic chromosome condensation by UBE3C expression — OVARY

Explore this box plot interactively →