UBE2V1

Across TCGA pan-cancer cohorts, UBE2V1 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated UBE2V1 data layer compared with 30 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher UBE2V1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated UBE2V1 expression acts as an unfavorable survival marker, although some lineages such as UCEC and HNSC show a favorable association.

UCEC, LSCC, and HNSC are the cancer types where UBE2V1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	All	1.000	0.908	.012	28	view →
LSCC	OS	Tertile	II,III,IV	0.382	0.817	.005	6	view →
HNSC	DFS	Median	III,IV	1.000	0.932	.038	3	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

UBE2V1–UCEC (OS)

Open the UCEC breakdown →