UBE2T

Across TCGA patient cohorts, UBE2T mutation is significantly associated with the RNA expression of many other genes, with 54 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UBE2T-associated genes across cancer lineages are USP9YP15, RPL22P6, and IGHV3OR16-9. Each is linked with UBE2T in more than 1 cancer types. Because this analysis shows association rather than direction, both UBE2T-to-partner and partner-to-UBE2T results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, USP9YP15 grouped by UBE2T-low versus UBE2T-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE2T→partner) and Y-score (partner→UBE2T) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	USP9YP15 →	+0.084	+8.471	<.001	.005	3	1
UCEC	RPL22P6 →	+0.111	+4.226	<.001	.008	3	1
UCEC	IGHV3OR16-9 →	+0.881	+3.738	.002	.006	3	1
UCEC	APOOP1 →	+0.136	+3.638	.001	.006	3	1
UCEC	IGHV1OR15-3 →	+0.141	+3.677	.009	.006	3	1
UCEC	RN7SL197P →	+0.227	+3.599	.002	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 54 associations by consensus.

USP9YP15 by UBE2T expression — BRCA

Explore this box plot interactively →