UBE2R2

Across TCGA patient cohorts, UBE2R2 protein abundance is significantly associated with the RNA expression of many other genes, with 14,080 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible UBE2R2-associated genes across cancer lineages are TOPORS, EXOSC3, and DCTN3. Each is linked with UBE2R2 in more than 5 cancer types. Because this analysis shows association rather than direction, both UBE2R2-to-partner and partner-to-UBE2R2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UBE2R2 versus TOPORS in LSCC, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE2R2→partner) and Y-score (partner→UBE2R2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TOPORS →	+0.511	+0.241	<.001	<.001	3	6
LSCC	EXOSC3 →	+0.571	+0.268	<.001	<.001	3	5
HNSC	DCTN3 →	+0.496	+0.219	<.001	.004	3	5
LSCC	ZCCHC7 →	+0.454	+0.263	<.001	<.001	3	5
LSCC	UBAP1 →	+0.555	+0.196	<.001	<.001	3	5
LSCC	ZBTB5 →	+0.615	+0.223	<.001	.005	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,080 associations by consensus.

UBE2R2 vs TOPORS — LSCC

Explore this scatter interactively →