UBE2R2

Across TCGA cell cohorts, UBE2R2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,033 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible UBE2R2-associated GO terms across cancer lineages are Protein monoubiquitination, Autophagosome organization, and Autophagosome assembly. Each is linked with UBE2R2 in more than 11 cancer types. Because this analysis shows association rather than direction, both UBE2R2-to-partner and partner-to-UBE2R2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein monoubiquitination grouped by UBE2R2-low versus UBE2R2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE2R2→partner) and Y-score (partner→UBE2R2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Protein monoubiquitination →	+0.092	+0.917	<.001	<.001	3	12
BLOOD_Myeloma	Autophagosome organization →	+0.071	+0.847	<.001	<.001	3	11
BLOOD_Myeloma	Autophagosome assembly →	+0.076	+0.933	<.001	<.001	3	11
URINARY_TRACT	Regulation of intracellular steroid hormone receptor signaling pathway →	+0.064	+0.674	<.001	.001	3	9
OESOPHAGUS	Ubiquitin-dependent protein catabolic process via the C-end degron rule pathway →	+0.120	+0.709	.003	<.001	3	9
BLOOD_Leukemia	Positive regulation of myoblast differentiation →	+0.074	+0.531	.002	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,033 associations by consensus.

Protein monoubiquitination by UBE2R2 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →