UBE2R2-AS1

Across TCGA pan-cancer cohorts, UBE2R2-AS1 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of UBE2R2-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where UBE2R2-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types UBE2R2-AS1 is over-expressed in tumor, although a few such as THCA and KIRC show the opposite, repressed pattern.

COAD, THCA, and KIRC are the cancer types where UBE2R2-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in UBE2R2-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	II,III,IV	+0.887	<.001	10	view →
THCA	All	All	−0.155	.003	4	view →
KIRC	Male	II,III,IV	−0.111	.006	4	view →
ESCA	All	All	+0.865	.007	3	view →
STAD	All	All	+0.519	.009	2	view →
CHOL	All	All	+0.353	.001	2	view →
PRAD	All	All	+0.295	.004	2	view →
LUSC	All	All	+0.238	.004	2	view →
BRCA	All	All	+0.170	.045	2	view →
LUAD	All	All	+0.247	.043	1	view →
LIHC	All	II,III,IV	+0.074	.029	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

UBE2R2-AS1–COAD

Open the COAD breakdown →