Across TCGA pan-cancer cohorts, UBE2Q2P11 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of UBE2Q2P11’s most consistent transcriptional readouts.
The strongest signal is observed in kidney chromophobe (KICH), where UBE2Q2P11 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types UBE2Q2P11 is over-expressed in tumor, although a few such as UCEC and PRAD show the opposite, repressed pattern.
KICH, UCEC, and PRAD are the cancer types where UBE2Q2P11 tumor–normal differential expression is most reproducible.