UBE2Q2L

Across TCGA pan-cancer cohorts, UBE2Q2L RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated UBE2Q2L data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher UBE2Q2L RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated UBE2Q2L expression acts as an unfavorable survival marker, although some lineages such as KIRP and LGG show a favorable association.

HNSC, KIRP, and DLBC are the cancer types where UBE2Q2L RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Quartile	All	0.465	0.634	<.001	58	view →
KIRP	DFS	Tertile	II,III,IV	0.940	0.203	.002	52	view →
DLBC	DFS	Tertile	III,IV	0.070	0.855	.008	28	view →
CHOL	DFS	Median	All	0.127	0.669	.009	21	view →
UVM	DFS	Quartile	III,IV	0.284	0.849	.001	17	view →
LGG	OS	Quartile	All	0.611	0.387	.001	16	view →
KIRC	DFS	Median	III,IV	0.843	0.640	.023	14	view →
GBM	DFS	Quartile	All	0.181	0.314	.003	12	view →
UCS	DFS	Tertile	III,IV	0.533	0.218	.007	12	view →
THCA	OS	Tertile	All	0.873	0.983	.033	12	view →
CESC	DFS	Tertile	III,IV	0.537	0.762	.029	10	view →
ESCA	OS	Quartile	All	1.000	0.110	.004	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

UBE2Q2L–HNSC (DFS)

Open the HNSC breakdown →