UBE2Q1

Across TCGA pan-cancer cohorts, UBE2Q1 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated UBE2Q1 data layer compared with 25 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher UBE2Q1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated UBE2Q1 expression acts as an unfavorable survival marker, although some lineages such as PDAC and LSCC show a favorable association.

PDAC, COAD, and HNSC are the cancer types where UBE2Q1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Quartile	II,III,IV	0.712	0.375	<.001	66	view →
COAD	DFS	Median	All	0.925	1.000	.017	48	view →
HNSC	OS	Tertile	IV	0.652	0.916	.004	23	view →
CCRCC	DFS	Tertile	All	0.622	0.865	.012	21	view →
LSCC	OS	Median	All	1.000	0.922	.009	18	view →
UCEC	DFS	Median	All	1.000	0.939	.030	2	view →
LUAD	DFS	Median	All	0.522	0.733	.030	2	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

UBE2Q1–PDAC (OS)

Open the PDAC breakdown →