UBE2Q1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, UBE2Q1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,412 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible UBE2Q1-associated GO terms across cancer lineages are Regulation of protein sumoylation, Cytosolic transport, and Pre-mRNA catabolic process. Each is linked with UBE2Q1 in more than 16 cancer types. Because this analysis shows association rather than direction, both UBE2Q1-to-partner and partner-to-UBE2Q1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein sumoylation grouped by UBE2Q1-low versus UBE2Q1-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE2Q1→partner) and Y-score (partner→UBE2Q1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_SCLCRegulation of protein sumoylation →+0.092+0.627.005.006217
UPPER_AERODIGESTIVE_TRACTCytosolic transport →+0.081+1.083<.001<.001315
BONEPre-mRNA catabolic process →+0.183+0.725<.001.002315
BREASTPositive regulation of TORC2 signaling →+0.123+1.321<.001<.001314
BONEResponse to dehydroepiandrosterone →+0.197+1.186<.001<.001314
LARGE_INTESTINEPositive regulation of protein sumoylation →+0.123+1.031<.001<.001314
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,412 associations by consensus.

Regulation of protein sumoylation by UBE2Q1 expression — LUNG_SCLC

Box plot of Regulation of protein sumoylation in UBE2Q1-low vs UBE2Q1-high samples in LUNG_SCLC.

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Exploration