UBE2Q1-AS1

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, UBE2Q1-AS1 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of UBE2Q1-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where UBE2Q1-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types UBE2Q1-AS1 is over-expressed in tumor.

BLCA, HNSC, and COAD are the cancer types where UBE2Q1-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in UBE2Q1-AS1 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
BLCAMaleAll+0.875<.00110view →
HNSCAllIII,IV+0.328<.00110view →
COADMaleII,III,IV+0.711<.0019view →
KIRCAllAll+0.334<.0019view →
LUADFemaleAll+0.647<.0018view →
BRCAAllII,III,IV+0.467<.0016view →
LUSCAllAll+0.519<.0015view →
LIHCAllAll+0.166<.0015view →
CHOLAllAll+1.741<.0014view →
STADAllAll+0.516<.0014view →
READAllAll+0.911.0062view →
ESCAAllAll+0.637.0082view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

UBE2Q1-AS1–BLCA

Tumor-vs-normal expression box plot for UBE2Q1-AS1 RNA in BLCA.

Open the BLCA breakdown →

Exploration