UBE2NL

Across TCGA patient cohorts, UBE2NL RNA expression is significantly associated with the go_rna of many other GO terms, with 4,846 significant associations in total. STAD shows the largest number of these associations.

The most reproducible UBE2NL-associated GO terms across cancer lineages are Mitochondrial translation, Maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), and Maturation of LSU-rRNA. Each is linked with UBE2NL in more than 12 cancer types. Because this analysis shows association rather than direction, both UBE2NL-to-partner and partner-to-UBE2NL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial translation grouped by UBE2NL-low versus UBE2NL-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE2NL→partner) and Y-score (partner→UBE2NL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Mitochondrial translation →	+0.047	+0.084	<.001	<.001	3	13
LAML	Maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.056	+0.147	<.001	.002	2	13
LAML	Maturation of LSU-rRNA →	+0.051	+0.176	<.001	<.001	3	12
STAD	Endoplasmic reticulum organization →	+0.033	+0.073	<.001	<.001	3	12
STAD	Mitochondrial gene expression →	+0.044	+0.100	<.001	<.001	3	11
LAML	Negative regulation of double-strand break repair via homologous recombination →	+0.054	+0.199	<.001	<.001	2	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,846 associations by consensus.

Mitochondrial translation by UBE2NL expression — STAD

Explore this box plot interactively →