UBE2NL

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, UBE2NL RNA expression is significantly associated with the go_rna of many other GO terms, with 1,985 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible UBE2NL-associated GO terms across cancer lineages are Leading strand elongation, Positive regulation of DNA replication, and Regulation of double-strand break repair. Each is linked with UBE2NL in more than 8 cancer types. Because this analysis shows association rather than direction, both UBE2NL-to-partner and partner-to-UBE2NL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Leading strand elongation grouped by UBE2NL-low versus UBE2NL-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE2NL→partner) and Y-score (partner→UBE2NL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
PANCREASLeading strand elongation →+0.167+0.050<.001<.00139
SOFT_TISSUEPositive regulation of DNA replication →+0.081+0.051<.001.00438
SOFT_TISSUERegulation of double-strand break repair →+0.053+0.053.003.00238
CNSLatent virus replication →+0.107+0.063<.001<.00137
CNSRelease from viral latency →+0.107+0.063<.001<.00137
LARGE_INTESTINERegulation of DNA-templated transcription initiation →+0.035+0.048.009.00937
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,985 associations by consensus.

Leading strand elongation by UBE2NL expression — PANCREAS

Box plot of Leading strand elongation in UBE2NL-low vs UBE2NL-high samples in PANCREAS.

Explore this box plot interactively →

Exploration