UBE2MP1

Across TCGA pan-cancer cohorts, UBE2MP1 Mutation is linked to patient survival in 6 of 34 cancer types, making it a survival-associated UBE2MP1 data layer compared with 22 for mass-spec protein.

The strongest signal is observed in brain lower grade glioma (LGG), where higher UBE2MP1 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated UBE2MP1 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

LGG, GBM, and SKCM are the cancer types where UBE2MP1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LGG	DFS	Median	All	0.080	0.833	<.001	12	view →
GBM	OS	Median	All	0.030	0.416	<.001	12	view →
SKCM	DFS	Median	All	0.237	0.760	.002	12	view →
UCEC	DFS	Median	All	1.000	0.622	.020	8	view →
ESCA	DFS	Median	III,IV	0.103	0.442	.021	6	view →
LUAD	OS	Median	All	0.117	0.380	.027	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

UBE2MP1–LGG (DFS)

Open the LGG breakdown →