UBE2MP1

Across TCGA patient cohorts, UBE2MP1 mutation is significantly associated with the RNA expression of many other genes, with 1,712 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UBE2MP1-associated genes across cancer lineages are IRX3, SARM1, and RNU6-271P. Each is linked with UBE2MP1 in more than 2 cancer types. Because this analysis shows association rather than direction, both UBE2MP1-to-partner and partner-to-UBE2MP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IRX3 grouped by UBE2MP1-low versus UBE2MP1-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE2MP1→partner) and Y-score (partner→UBE2MP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	IRX3 →	+0.946	+3.471	.002	.002	3	3
COAD	SARM1 →	-0.359	-3.571	.004	.002	3	3
READ	RNU6-271P →	+0.455	+4.653	<.001	.007	3	2
READ	TRAV32 →	+0.117	+4.925	.002	.004	3	2
SKCM	ACYP1 →	+0.674	+3.491	.003	.002	3	2
BLCA	LINC00904 →	+0.107	+4.788	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,712 associations by consensus.

IRX3 by UBE2MP1 expression — LUSC

Explore this box plot interactively →